OX40L-JAG1–Induced Expansion of Lineage-Stable Regulatory T Cells Involves Noncanonical NF-κB Signaling
نویسندگان
چکیده
منابع مشابه
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis
CD40, a member of the tumor necrosis factor (TNF) receptor family, plays an essential role in T cell-dependent immune responses. Because CD40 is widely expressed on the surface of tumor cells in various B cell malignancies, deregulated CD40 signaling has been suggested to contribute to lymphomagenesis. In this study, we show that B cell-specific expression of a constitutively active CD40 recept...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2019
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1900530